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Pathogen Access and Benefit-Sharing
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Pathogen Access and Benefit-Sharing

Deadlocked WHO Pandemic Agreement annex; DRC shares sequences with no treaty-guaranteed vaccine access as negotiations slip to 2027.

The pathogen-sharing annex missed another Deadline on 18 September 2026, when the eighth Geneva session closed without an agreed text, leaving the treaty it completes unsignable until at least May 2027.

Last refreshed: 4 October 2026 · Appears in 1 active topic

Key Question

Can PABS survive being bypassed in real time as DRC shares sequences with no return guarantee?

Timeline for Pathogen Access and Benefit-Sharing

#14 18 Sept

Remained without an agreed text after IGWG8

Pandemics and Biosecurity: WHO talks on pathogen sharing fail again
#11 17 Jul

Missed its fourth adoption deadline at IGWG7

Pandemics and Biosecurity: PABS annex slips a fourth deadline
#9 6 Jul
#6 5 Jun
View full timeline →

Background

Pathogen Access and Benefit-Sharing (PABS) is the annex that would make the WHO Pandemic Agreement work. It pairs two duties. Countries would share pathogen samples and genetic sequences quickly during an emergency. Manufacturers that use them would return a share of the resulting vaccines and medicines to the countries that supplied them. Until the annex passes, governments cannot sign the May 2025 Agreement at all.

The annex has been the main fault line since treaty talks began in 2022. Lower-income countries, led by the African Group, demand mandatory dose-sharing, technology transfer and intellectual-property waivers as the price of rapid sharing. High-income states and industry prefer voluntary, market-based commitments. Knowledge Ecology International has proposed tying benefit-sharing to a product's market registration rather than to proof that shared material was used.

The dispute predates the 2025 treaty by almost 20 years. Indonesia stopped sharing H5N1 samples with WHO in late 2006, on the ground that the resulting vaccines cost more than it could pay; the voluntary Pandemic Influenza Preparedness Framework followed only in May 2011. Lower-income countries regard that model as having failed them during COVID-19.

Key Issues
Treaty talks

The annex keeps missing its deadlines

The 79th World Health Assembly deferred adoption of the annex on 19 May 2026, moving the target to May 2027 or a special session. The seventh negotiating session opened on 6 July under a 17 July Deadline set by Brazil's President Lula and WHO's Tedros, and closed with no text, the fourth deferral since May 2025. The Africa Group, speaking through Algeria, backed a federated network of national laboratories with binding access conditions; the EU and other industrialised states backed a more centralised hybrid model.

The eighth session closed on 18 September without a text either. On 25 September a UN General Assembly declaration on pandemics left the annex's May 2027 target unchanged.

Ebola test case

Bundibugyo exposes the missing guarantee

The Bundibugyo Ebola emergency, declared on 17 May 2026, is the first test of what the absent annex costs. No licensed vaccine, antibody or antiviral works against the Bundibugyo species; Ervebo, Inmazeb and Ebanga all target Zaire ebolavirus.

DR Congo shares the virus's sequence data in real time through existing channels. Without the annex, nothing binds a manufacturer to return doses of any product built on it. A $62m Coalition launched on 1 June to fast-track three Bundibugyo vaccines, which needed 12 to 18 months before any human dosing. Any vaccine that results will reach the country that supplied the samples on commercial or donor terms, not by treaty right.

Common Questions

Reference

What is PABS and why is it blocking the WHO Pandemic Agreement?
PABS is the unresolved annex setting rules for pathogen sample-sharing and equitable distribution of resulting vaccines. The Agreement adopted at WHA78 in May 2025 cannot be signed under Article 31(2) without PABS resolved. WHA79 deferred adoption to 2027.Source: WHO
Why do developing countries want mandatory benefit-sharing in the pandemic treaty?
COVID-19 showed that voluntary arrangements leave lower-income countries last in the vaccine queue despite contributing pathogen samples. The African Group argues mandatory PABS is the only mechanism that prevents a repeat.Source: African Group, WHO negotiations
What is the disagreement between the Africa Group and the EU over the pandemic treaty?
At IGWG7 the Africa Group, represented by Algeria, backed a federated model of distributed national and regional laboratories under binding conditionalities. The EU and other industrialised states backed a hybrid model with more centralised infrastructure and looser access conditions.Source: WHO/IGWG7
When will the PABS annex to the WHO Pandemic Agreement be finalised?
IGWG7 closed on 17 July 2026 without agreed text, the fourth deferral. The next session, IGWG8, is set for 14-18 September 2026, with formal adoption still targeted for WHA80 in May 2027.Source: WHO
Is DRC receiving vaccines in exchange for sharing Ebola sequences?
Not under any treaty obligation. DRC shares Bundibugyo sequence data under existing WHO mechanisms, but the PABS annex that would guarantee benefit-sharing in return remains unresolved after IGWG7 closed on 17 July 2026 without agreed text.Source: WHO/CEPI
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