
Longwall Ventures
Oxford deeptech VC writing £500k-£2m cheques; Fund 1 backed OrganOx, sold to Terumo for $1.5bn.
Last refreshed: 4 July 2026 · Appears in 1 active topic
Is Longwall Ventures' 19x OrganOx exit a repeatable formula or a once-in-a-decade outlier?
Timeline for Longwall Ventures
Mentioned in: £6.5bn guarantee targets the debt tier
UK Startups and InnovationMentioned in: Spinout deals fall 33% as seed dries up
UK Startups and InnovationMentioned in: Seedcamp closes its record $320m fund
UK Startups and InnovationMentioned in: IMU raises £40m to read blood
UK Startups and InnovationAnnounced £50m BBB cornerstone and £86.2m first close of Fund 4
UK Startups and Innovation: State £50m backs the tier funds skipWhat is the Longwall Ventures OrganOx exit and why does it matter for UK deeptech?
How much has the British Business Bank committed to Longwall Ventures and for what purpose?
What sectors does Longwall Ventures invest in?
Background
The British Business Bank made a £50m cornerstone commitment to Longwall Ventures Fund 4 on 27 May 2026 via its Enterprise Capital Funds programme. Fund 4 targets £100m total and had reached £86.2m at announcement. The fund writes £500,000 to £2m cheques into 14 to 16 early-stage deeptech companies across advanced manufacturing, clean energy, defence and life sciences.
Founded in Oxford around 2008-2011, Longwall Ventures has built one of the UK deeptech sector's most credible track records. Its Fund 1 backed OrganOx, the Oxford spinout maker of liver perfusion devices, which was sold to Japan's Terumo in 2025 for $1.5bn, a 19.2x return for the British Business Bank on its original commitment and the largest-ever acquisition of an Oxford University spinout.
Longwall targets what it calls the 'tier gap': the space between university proof-of-concept grants and institutional Series A rounds, where capital-intensive deeptech companies most frequently fail. The BBB's continued commitment across four funds reflects the long-term Nature of deeptech investing; OrganOx took 17 years from founding to exit. The tier gap widened further in the following weeks: British Business Bank data published 2 July showed university spinout equity deals down 33% by count and 51% by value in 2025, with over a third of rounds closing below £500,000, the exact evidence for why the Bank keeps re-upping rather than expecting the gap to close on its own.